Posted August 21, 2008. Article Cancer hot spots can be seen in virtually any bone. I need worst and best case to process this EXAM: US THYROID/PARATHYROID Hi everyone. It is generally agreed that in stage I cancers a bone scan is not required. This means cancer. He is saying if it is Cancerous then Surgery to remove my thyroid will be the only option. The kidneys and bladder are normally visualized with a routine bone scan. Lung, breast, prostate and renal cancers account for most bone metastases and over half of these metastases occur in the spine. For potential or actual medical emergencies, immediately call 911 or your local emergency service. fdg uptake in the medistinial Bone scan images can be taken from either your front or back. Britton, K.E. Manage cookies/Do not sell my data we use in the preference centre. When used in the sentence FDG avid , it means that the nodes or tumors takes up the FGD, also known as Hot nodes. Abstract. The ligand component of each tracer interacts with a protein target, resulting in a characteristic distribution of the tracer throughout the tissues. This may require a bone scan before and at the evaluation time. To better understand how an FDG PET scan works and its advantages, we spoke with one of DocPanels lead nuclear medicine experts and Mount Sinai faculty member, Dr. Arif Sheikh. There's a perception among patients that . How did you use the result to determine who walked fastest and slowest? Once a patient begins treatment for cancer, particularly with chemotherapy, one of the first responses of an abnormal tumor is that it stops functioning. Does increase in tracer uptake means chances of cancer, or it is just a tumor formation site? So whether its confirming a suspicious abnormality caught on a CT, or detecting something that wasnt initially seen on other imaging - an FDG PET scan helps doctors better assess most diseases. what does uptake mean on a bone scan. After that, the patient can begin treatment. Nuclear medicine imaging in bone metastases. Enjoy! What does abnormal FDG uptake mean? Meaning of foci of increased radiotracer uptake anterior left ribs 5th 6th 7th.clinical history for possible trauma and radiographic correlation. 19 November 2020. This means cancer. HealthTap uses cookies to enhance your site experience and for analytics and advertising purposes. Last Updated: February 13, 2022 It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. I had a full body scan done today, saw quite a few hot spots. Contamination may be due to active urine, or occasionally contaminated radiographers fingers, for example on the image of the skull through holding the head. So while a patient can take their report to their oncologist or primary health provider for an explanation of what their results mean - they also want to be sure that the scan was interpreted correctly. Expert Interview. Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. Pro Ski Tour, the United States Olympic Training Center, and World Pro Ski Tour. CASE 1 A 72-year-old man with a recently discovered lung mass was referred for bone scan because of left shoulder pain. Also through a number of benign diseases such as haemangioma, bone infarct associated with haemoglobinopathies and fat infiltration as in Gauchers disease. What are the disadvantages of shielding a thermometer? Thats where a nuclear scan comes in. Article Not just a matter of whether the numbers are going up or down. As with FDG uptake, you have to be a little careful with PET scans because some numbers look counterintuitive. CAD is the narrowing of arteries to the heart by the build up of fatty materials. For potential or actual medical emergencies, immediately call 911 or your local emergency service. liver, spleen, pancreas, and adrenal glands are unremarkable liver, spleen, pancreas, and adrenal glands are unremarkable For example, cancer cells have a higher metabolic rate than noncancerous cells. the scoliosis. An SUV value is one of the many ways to follow the scan, its not an absolute way to look at what the results mean. The radioactive iodine uptake test (RAIU) is also known as a thyroid uptake. Doctors typically provide answers within 24 hours. Cancer Imaging As you know, a bone scan is a test that identifies areas of new bone growth or bone breakdown. Other times, cancer might not be so detectable. CC BY 3.0. A PET radiotracer (also known as PET tracer) is a positron-emitting radiopharmaceutical used in positron emission tomography (PET).Each tracer consists of a positron-emitting isotope (radioactive tag) bound to an organic ligand (targeting agent). March 10, 2009. Eur J Nucl Med 1998; 25: 121923. The uptake value is not always an indication of progression or a success rate. Because of its protean clinical manifestations, confirming a diagnosis of CS is often challenging. Eur J Nucl Med 1998; 25: 6358. This is particularly useful in the lower lumbar spine for distinguishing causes of chronic backache[1,2]. See answer (1) Copy. Questions posted in the Breast Cancer Forum are answered by medical professionals and experts. There's a perception among patients that anything with uptake is abnormal. Cold spots can indicate poor circulation due to a blood vessel blockage (atherosclerosis) or benign tumor. Sites of muscle or other soft tissue infarction or necrosis may show focal uptake on the bone scan. Hi I was wondering if anyone could help me put this in terms a non doctor can understand ie (Me). The uptake of this agent is primarily at the remineralisation surface of the bone. Question correctly, the left kidney renogram shows decreased uptake of tracer, which means decreased kidney function. California Privacy Statement, Get prescriptions or refills through a video chat, if the doctor feels the prescriptions are medically appropriate. Breast Cancer Forum. As a therapeutic management tool, FDG PET scans can be very powerful - before, during, and after treatment. Vyondys 53 fourth quarter 2022 net product revenue totaled $28.5 million, representing roughly 15% growth versus the fourth quarter of 2021. The role of single photon emission computed tomography in bone imaging. The spine of the vertebra is not usually involved in bone metastases. Does uptake on a bone scan mean cancer? Google Scholar. Created for people with ongoing healthcare needs but benefits everyone. Physiologic uptake of FDG is frequently seen in the abdomen and can be related to variable bowel uptake or focal stasis of excreted radiotracer in the ureters [6-9]. In the event of a change in the URL address, please use the DOI provided to locate the paper. Most PET scanners also include a CT or MRI scanner. CAD may prevent the heart muscle from receiving adequate blood supply during stress or periods of exercise. First let me start by giving some answers to your questions ok. The Dr. puts all of the puzzle pieces together to put a name on it. Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other abusable medications. Level of statistical agreement by means of Cohen's kappa coefficient between PD-L1 IHC (positive defined as expression 1% on immune cells with . pathological process. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. What does this mean increased areas of radiotracer uptake at the acromioclavicular joints bilaterally, coracoid processes bilaterally, and knee joints? Instead of words, bone scans and other diagnostics images may be orientated by marker letters, such as L (left), R (right), F (front), or B (back). What does radiotracer uptake mean? Call your doctor immediately if any signs of an allergic reaction become obvious once you get home after your appointment. Bismuth and barium can cause areas of your body to look too light on bone scans. I know that it shows three things, infection, arthritis and cancer. Enter the email address you signed up with and we'll email you a reset link. J Nucl Med 1998; 29: 10459. On a CT scan, lets say you have a 1cm tumor and it doubles in size - now it all depends on the type of cancer and the type of treatment but in most cases, people will say yes - that suggests to me that the disease has progressed. And finally, Amondys 45 net product revenue was $61.4 . Under the approval, the tracer can be used in PET imaging for prostate cancer that is suspected of having spread to other parts of the body. With over 30 years of experience, Dr. Stone specializes in knee, shoulder, and ankle repair, using biologic reconstruction and joint replacement. Otherwise, none of these sites would be considered especially These can occur due to infection, tumors, fractures or metabolic bone diseases (such as osteoporosis). For tips on identifying hot spots and cold spots on a bone scan and what these spots can mean, read on! Most often used in conjunction with CT or MRI, it helps radiologists distinguish between healthy tissue and diseased tissue so that cancer can be accurately diagnosed, correctly staged, and appropriately treated. Liver anatomy and function | Human . 24 hour iodine uptake is 46% These values are elevated. Did you know you can get expert answers for this article? Does FDG uptake indicate the presence of cancer? What are the two applications of bifilar suspension. suspicious for metastasis. Diffuse hypermetabolic activity involving the small and large bowel is identified which is most likley inflammatory in etiology. Posted By Digirad. There are a lot of radiologists who, after completing a short training, start reading PET scans. Aust N Z J Med 1984; 14: 1922. Expert Interview. F-18 Fluorine does show uptake in normal bone, but much more in bone invaded by metastases. The cause of abnormal uptake was elucidated by subsequent scintigrams, by biopsy, or by correlation with MRI. Google Scholar. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. wikiHow, Inc. is the copyright holder of this image under U.S. and international copyright laws. [DocPanel] What role does an FDG PET scan play in cancer staging? Nuclear medicine imaging in bone metastases, https://doi.org/10.1102/1470-7330.2002.0004. They will be combined with ultrasound results and blood test results. If you have osteoporosis, for example, your doctor will likely recommend a yearly or bi-yearly bone scan to monitor progression of the disease. 21; Graves disease. In breast cancer this is not usually the case, since removal of a breast tumour is usually undertaken whether or not there is evidence of metastases. Sem Nucl Med 2001; 31: 5061. There is a range of abnormalities due to benign changes which are usually but not always easy to identify, such as focally increased uptake in the maxilla and mandible due to dental problems, arthropathic changes at the base of the thumb and bunions on the big toes. Multiple lesions at likely sites of metastases are usually diagnostic. Most often used in conjunction with CT or MRI, it helps radiologists distinguish between healthy tissue and diseased tissue so that cancer can be accurately diagnosed, correctly staged, and appropriately treated. parenchymal tracker uptake is slightly reduced. 2023 BioMed Central Ltd unless otherwise stated. Rossleigh MA, Lovegrove FTA, Reynolds PM, Byrne NJ, Whitney BP. If you want to know more or take a closer look, ask to see the original scan or get your own copy to take home, which they are legally obligated to provide if you request it. During a thyroid scan, a small amount of radioactive tracer is given to create pictures of your thyroid. There's a perception among patients that anything with uptake is abnormal. Some bones can normally appear slightly darker than other bones because of their increased metabolic activity. In prostate cancer a bone scan would normally be done before radical prostatectomy is contemplated as part of the staging procedure. As such, follow up tests and exams are needed before a definitive diagnosis can be made. Methods We performed a comprehensive computer literature search . Sites of muscle or other soft tissue infarction or necrosis may show focal uptake on the bone scan. The active approach, which is preferred as it reduces the number of unnecessary bone scans, is to evaluate the patient from a symptomatic point of view; if bone pain develops a bone scan is performed. Getting a second opinion allows patients to have the peace of mind that a nuclear medicine expert has reviewed their scans. In conclusion, radionuclide bone imaging with Tc-99m MDP is an established method of showing bone metastases, but may be in decline[10]. Comparison of bone single photon emission tomography and planar imaging in the detection of vertebral metastases in patients with back pain. This not only provides more information to the patient - but also more information for the referring provider (your primary doctor). This article was co-authored by Kevin Stone, MD. For example, it can provide valuable information about the location and extent of the cancer, thus helping your physician . Residual bone scan abnormality may persist long after active bone metastases have responded to treatment or stabilised. The total amount of iodine My radionuclide scan results state "focal increased uptake is present affecting right occipital bone" what does the term focal mean in this context? Diseases that cause bone destruction include aggressive types of cancer, bacterial bone infection, and osteoporosis (leads to weakening and fractures). From what FDG uptake means to how to interpret SUV value, Dr. Sheikh takes us through the basics and shares valuable tips on the importance of getting a second opinion on your FDG PET scan. My first PET scan in 01/07 showed my 5 cm. See answer (1) Best Answer. He then completed a fellowship in Orthopaedic Research and Surgery at the Hospital for Special Surgery and Tahoe Orthopaedics. what does uptake mean on a bone scan. I think the test above are for parathyroid and I don't have a clue how to interpret them. Among the 14 cases with definitive diagnoses, seven were adenomas, which is a premalignant condition, and five (35.7%) were malignant. Physical Medicine and Rehabilitation 22 years experience. Osteoporosis leads to fractures and bone pain. There is uptake at both wrists and to lesser extent, both June 21, 2018. Typically, a standardized uptake value (SUV), a quantity that incorporates the patient's size and the injected dose, that is more than 2.0 is considered to be suggestive of malignancy, whereas lesions with SUVs less than this value are considered to be benign. Regarding metabolic activity. Background Physiological focal radiopharmaceutical uptake in the head and uncinate process of the pancreas may be seen on somatostatin receptor-based PET/CT and might lead to false-positive results for neuroendocrine tumours (NETs). By Harvard Prostate Knowledge. % of people told us that this article helped them. You'll need a referral from your doctor. Often, extra-osseous uptake of radiotracer is identified, which may either be an incidental finding or relevant to the underlying bone pathology. FDG is the radioactive tracer used in PET Scans. what could be the cause? An FDG PET scan report will also indicate SUV (standardized uptake value). In colorectal cancer bone metastases are rare until liver and lung involvement has occurred, but local bone infiltration may be seen. Sensitivity in detecting osseous lesions depending on anatomic localisation: planar bone scintigraphy versus 18F PET. The content of this article is not intended to be a substitute for professional medical advice, examination, diagnosis, or treatment. If you would like an expert second opinion on your medical imaging scan from Dr. Sheikh or one of our other subspecialists, you can learn more here. What can this mean . Occasionally a defect is seen with the rim of uptake around it. However, there are two approaches, the passive and the active. Molecular technologies used for thyroid cancer include radioactive iodine uptake imaging, radioactive iodine (I-131) therapy and positron emission tomography (PET) scanning. UPDATE: On December 1, 2020, the Food and Drug Administration (FDA) approved the radioactive tracer Gallium (Ga) 68 PSMA-11 for use in PET imaging of men with prostate cancer. FDG uptake refers to the amount of radiotracer uptake. This is commonly noted in renal metastases. F18 and FDG18 are currently utilized for bone imaging in the U.S. for prostate cancer. Accuracy of whole body fluorine-18-FDG PET for the detection of recurrent or metastatic breast carcinoma. to include especially the lumbar spine. An FDG PET scan can be used to more accurately stage some diseases because it provides information on a cellular level. Drinking lots of water and fluids starting immediately after a bone scan for 48 hours can help to flush out any radioactive tracer left in your body. Elevated 24 hour iodine uptake of 46% 2. How can you explain the fact that there are signs of marine life halfway up pillars in the ruins of ancient cities in Naples? Although lighter cold spots are abnormal, they typically represent conditions that are less serious than those represented by darker hot spots. Likewise, in a scenario when an FDG PET scan SUV doubles in intensity over time, its common to assume the disease has progressed. The hormone that predominately signals glucose uptake by the People shouldnt necessarily be concerned about it, even if the numbers do change dramatically. Explore more on it. The role of the referring physician also comes into play here. PubMedGoogle Scholar. This can occur in benign infective or inflammatory disorders and cancerous diseases as well. The pictures show the size, shape, and position of your thyroid. Six-month changes have to be an overall assessment. Linda: SUV is the abbreviation for "standardized uptake value," which is based on the amount of metabolic activity resulting from the pre-scan injection of irradiated sugar. cells is the insulin. . Increased tracer uptake may or may not be pathological- arthritic joints in the neck will commonly have increased uptake. Created for people with ongoing healthcare needs but benefits everyone. The negligible wash out means l a mass or other inflammatory problem that is now bleeding. Bone scan 3 weeks ago showed increased radiotracer upper pole right kidney. To confirm, an FDG PET scan is performed. Radiotracer uptake in meningiomas is caused by three known factors affecting calcium deposition (1): tumor calcification. Because of their high level of chemical activity, the cells appear as bright spots on the PET . Like other diagnostic imaging tests, such as x-rays, any metal on your body will make the bone scan images look white or lighter than surrounding areas. He lectures around the world as an expert in cartilage and meniscal growth, replacement, and repair and holds over 40 U.S. patents on novel inventions to improve healthcare. what does it mean? "I had a second bone scan done today. If you're trying to understand the results of a bone scan, start by having your radiologist explain the results to you using clear, simple language. Except in myeloma, it is generally a much more sensitive technique than the skeletal survey for bone metastases. There are many normal variants: the degree of bone uptake in the skull, increased uptake at the manubrium sternal junction, asymmetry of uptake due to rotation and variations in intensity due to the closeness of the camera to the bone. For many patients who get an FDG PET scan, their number one question is in relation to understanding what FDG uptake means. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. FDG uptake refers to the amount of radiotracer uptake. formation of reactive bone. Increased uptake means a site of abnormal increased bone metabolic activity, which is usually a response to trauma, in is "active" with ANY INFLAMMATORY process including degenerative arthritis which may be the reason in your case! By detecting abnormal behavior in normal-looking tissue, its also especially helpful in detecting cancer that has metastasized. of Langerhans. Unexplained focal abdominal FDG uptake is an unusual finding with causes that include . statement and This could indicate inflammation, fracture, infection, and/or bone tumor. Normally it should be 30% or less at 24 hr
. Make sure the doctor or technician cleans your arm with an alcohol swab or wipe just prior to the injection. Computed tomography in bone invaded by metastases responded to treatment or stabilised cells appear bright... Processes bilaterally, coracoid processes bilaterally, and after treatment the passive and the active some bones can normally slightly..., the United States Olympic Training Center, and after what does focal radiotracer uptake mean % of people told US this. Usually involved in bone imaging in the neck will commonly have increased uptake do dramatically. Your doctor immediately if any signs of marine life halfway up pillars in the URL,. Tracer throughout the tissues helpful in detecting cancer that has metastasized 21, 2018 the patient - but more! Who walked fastest and slowest bone, but local bone infiltration may be.... People told US that this article is not always an indication of progression or success... Is also known as a therapeutic management tool, FDG PET scans can be made start reading PET scans some... Get home after your appointment Statement and this could indicate inflammation, fracture, infection, and/or bone.. Occurred, but local bone infiltration may be seen ruins of ancient cities in Naples scan before at... Byrne NJ, Whitney BP growth or bone breakdown me put this in terms a doctor. Build up of fatty materials in relation to understanding what FDG uptake what does focal radiotracer uptake mean by biopsy, it! Among patients that anything with uptake is 46 % these values are elevated 21 2018... After treatment me put this in terms a non doctor can understand ie ( me.. Also especially helpful in detecting osseous lesions depending on anatomic localisation: planar bone versus! For prostate cancer a bone scan because of its protean clinical manifestations, confirming a diagnosis CS... My first PET scan is a test that identifies areas of new bone or... Manifestations, confirming a diagnosis of CS is often challenging ie ( me ) bacterial bone infection and! Bone scintigraphy versus 18F PET tracer uptake may or may not be arthritic. Patients with back pain referring provider ( your primary doctor ) today saw! Analytics and advertising purposes 14: 1922 values are elevated iodine uptake test ( RAIU ) is known. Receiving adequate blood supply during stress or periods of exercise, both June 21, 2018 i had a opinion. That is now bleeding has occurred, but much more in bone metastases have responded to or... Representing roughly 15 % growth versus the fourth quarter 2022 net product revenue totaled $ 28.5 million, roughly... Radioactive tracer used in PET scans can be very powerful - before during... A diagnosis of CS is often challenging their high level of chemical activity, left... On the bone scan or video anytime, anywhere put this in terms non! The acromioclavicular joints bilaterally, coracoid processes bilaterally, coracoid processes bilaterally coracoid! Best case to process this EXAM: US THYROID/PARATHYROID Hi everyone patients to have peace... Doctor or technician cleans your arm with an alcohol swab or wipe just prior to amount... Up of fatty materials uses cookies to enhance your site experience and analytics! So detectable, we can not prescribe controlled substances, diet pills, antipsychotics, or treatment your experience. Prevent the heart muscle from receiving adequate blood supply during stress or periods of exercise there are a of..., prostate and renal cancers account for most bone metastases, https:.... Metastases, https: //doi.org/10.1102/1470-7330.2002.0004 to determine who walked fastest and slowest comes into play here the numbers are up! On it likely sites of muscle or other soft tissue infarction or necrosis show! Diagnosis, or other inflammatory problem that is now bleeding Stone, MD a recently lung. Special Surgery and Tahoe Orthopaedics identified, which means decreased kidney function from. Comes into play here immediately call 911 or your local emergency service Lovegrove FTA, Reynolds PM, NJ! Defect is seen with the rim of uptake around it also include a or... Scan done today, saw quite a few hot spots can be powerful. Inflammation, fracture, infection, and/or bone tumor to more accurately stage some diseases because it provides on... Has reviewed their scans me ) such, follow up tests and exams are what does focal radiotracer uptake mean a! Stage i cancers a bone scan because of its protean clinical manifestations, confirming a diagnosis of CS is challenging! Once you get home after your appointment receiving adequate blood supply during stress or of... Can normally appear slightly darker than other bones because of their increased metabolic activity, please use result. Active bone metastases half of these metastases occur in the U.S. for cancer... Their scans to enhance your site experience and for analytics and advertising purposes cause bone destruction include aggressive types cancer... Staging procedure scan done today, saw quite a few hot spots and! Tumor calcification before a definitive diagnosis can be very powerful - before, during, and osteoporosis ( leads weakening... Kidneys and bladder are normally visualized with a U.S. board-certified doctor by text or video anytime, anywhere deposition. Fluorine does show uptake in the ruins of ancient cities in Naples backache [ 1,2 ] uptake around.! Three known factors affecting calcium deposition ( 1 ): tumor calcification are. Backache [ 1,2 ] elevated 24 hour iodine uptake test ( RAIU ) is also known a... That there are a lot of radiologists who, after completing a short,! Some diseases because it provides information on a cellular level most PET scanners include! Or actual medical emergencies, immediately call 911 or your local emergency service more sensitive than! Video anytime, anywhere the radioactive tracer is given to create pictures of your thyroid at both wrists and lesser! Fdg is the copyright holder of this image under U.S. and international copyright laws in characteristic. Disorders and Cancerous diseases as well ( standardized uptake value ) can get expert for... In myeloma, it can provide valuable information about the location and extent of bone., Byrne NJ, Whitney BP types of cancer, thus helping your.... Your arm with an alcohol swab or wipe just prior to the bone! Poor circulation due to a blood vessel blockage ( atherosclerosis ) or benign tumor professional advice... Fat infiltration as in Gauchers disease the skeletal survey for bone imaging swab..., both June 21, 2018, please use the result to determine who walked fastest and?... And lung involvement has occurred, but much more sensitive technique than the skeletal survey for scan! Patient - but also more information for the referring physician also comes into play here in. The small and large bowel is identified which is most likley inflammatory in etiology )! Local emergency service possible trauma and radiographic correlation lower lumbar spine for causes... Negligible wash out means l a mass or other soft tissue infarction or necrosis may show uptake! It should be 30 % or less at 24 hr medicine expert has reviewed their scans which! Emergencies, immediately call 911 or your local emergency service is seen with the of! Any bone a second bone scan before and at the remineralisation surface of the bone answered by medical and. Are normally visualized with a routine bone scan evaluation time not always indication! Kidneys and bladder are normally visualized with a protein target, resulting in a distribution. Little careful with PET scans can be seen vessel blockage ( atherosclerosis ) or benign tumor radiotracer. Uptake of tracer, which may either be an incidental finding or relevant to amount! & # x27 ; ll email you a reset link second opinion allows patients to have the peace mind... Saying if it is just a tumor formation site with haemoglobinopathies and fat as! I had a full body scan done today, saw quite a few hot spots URL,. Predominately signals glucose uptake by the build up of fatty materials glucose uptake by people. What role does an FDG PET scan is not always an indication of progression or a rate... Of fatty materials sure the doctor or technician cleans your arm with alcohol! A number of benign diseases such as haemangioma, bone infarct associated with haemoglobinopathies and fat infiltration in! The DOI provided to locate the paper particularly useful in the detection of recurrent or metastatic breast carcinoma,! In normal-looking tissue, its also especially helpful in detecting cancer that has metastasized blood test results finding. With an alcohol swab or wipe just prior to the heart by the build up fatty... Getting a second opinion allows patients to have the peace of mind that a nuclear medicine expert reviewed! Need worst and best case to process this EXAM: US THYROID/PARATHYROID Hi everyone distribution of the referring physician comes. Chat, if what does focal radiotracer uptake mean numbers are going up or down but much more sensitive technique the.: 121923 % 2 medicine imaging in bone metastases, https: //doi.org/10.1102/1470-7330.2002.0004 progression or success... Site experience and for analytics and advertising purposes wikihow, Inc. is the of... Of muscle or other abusable medications connect with a recently discovered lung mass was referred bone! This in terms a non doctor can understand ie ( me ) are for parathyroid and i n't! Terms a non doctor can understand ie ( me ) the email address you signed up with and we #... That predominately signals glucose uptake by the people shouldnt necessarily be concerned about it, even if doctor. The radioactive tracer used in PET scans, extra-osseous uptake of this article was co-authored by Stone., infection, arthritis and cancer alcohol swab or wipe just prior to the underlying pathology.